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Mortality with different antipsychotic medications..

January 10, 2013

The “truth” seems to be that “newer”, better antipsychotics are easily just more deadly. 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study) shows that likelyhood of death is:

  1. Clozapine HR 0.74
  2. Perphenanize HR 1.00
  3. Olanzapine (Zyprexa) HR 1.13
  4. Thioridazine HR 1.14
  5. Risperidone HR 1.14
  6. Haloperidol HR 1.37
  7. Quetiapine (Seroquel) HR 1.45

So this, and another figure clearly shows that Seroquel is one of the worst medication you can get. It is one of the deadliest medication and the best ones are clozapine, perphenazine, haloperidol and maybe zyprexa. In terms of suicide, the situation is:

  1. Clozapine HR 0.34
  2. Haloperidol HR 0.61
  3. Thioridazine HR 0.93
  4. Olazapine HR 0.94
  5. Perphenazine HR 1.00
  6. Risperidone HR 1.12
  7. Quetiapine (Seroquel) HR 1.58

Again showing that Risperidone (Risperdal) and Quetiapine (Seroquel) are one of the deadliest drugs while Clozapine and Haloperidol are the safest in terms of suicide (treatment in a hospital where you cannot do suicide?).

So it seems these figures are backwards as seroquel is maybe the least dangerous drug if used properly. Thought seroquel is sometimes given to people that are just disliked (very mild “go away” drug) so it means that you are more likely to be treated badly and you die to the treatments or to suicide or something.


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